Microencapsulación de compuestos de actividad biológica

Authors

  • Mary Lopretti Departamento de Bioprocesos y Biotecnología, Laboratorio Tecnológico del Uruguay (LATU) Laboratorio de Bioquímica y Biotecnología (CIN), Facultad de Ciencias, Universidad de la República,(UDELAR), Uruguay
  • Filomena Barriero Instituto Politécnico de Bragança, Portugal
  • Isabel Fernandes Instituto Politécnico de Bragança, Portugal
  • Agustin Damboriarena Departamento de Bioprocesos y Biotecnología, Laboratorio Tecnológico del Uruguay (LATU), Uruguay
  • Carolina Ottati Departamento de Bioprocesos y Biotecnología, Laboratorio Tecnológico del Uruguay (LATU), Uruguay
  • Alvaro Olivera Unidad de Microscopía Electrónica de Transmisión, Facultad de Ciencias,Universisad de la República (UDELAR), Uruguay

DOI:

https://doi.org/10.26461/02.06

Abstract

The microencapsulation process of agents with biological activity (such as DNA, pharmaceuticals, proteins, probiotics, enzymes, etc.), from the technological view, could be defined as the coating process of those agents, under a molecular form, solid particles, or liquid globules, with materials of different nature, that gives particles particles of micrometric size. One of the most used natural polymers for the production of microspheres is chitosan (?-1,4-glucosamine). Various methods have been proposed for the production of microcapsules, divided into three groups: physical processes, chemical processes, and physico-chemical processes. In this work, it were assayed different methodologies for the production of chitosan microspheres and microcapsules. Depending on the methodology used, were obtained differente types of spheres in reference to size and density. The microparticles produced were evaluated with optic microscopy, scanning electronic microscopy, so as were evaluated its stability and liberation of the encapsulated agent.

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How to Cite

Microencapsulación de compuestos de actividad biológica. (2011). INNOTEC, 2 ene-dic, 19-23. https://doi.org/10.26461/02.06

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